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Page 1
Porphyromonas gingivalis and its CRISPR-Cas system.
Chen T, Olsen I. Chen T, et al. J Oral Microbiol. 2019 Jul 3;11(1):1638196. doi: 10.1080/20002297.2019.1638196. eCollection 2019. J Oral Microbiol. 2019. PMID: 31303969 Free PMC article. Review.
The clustered regularly interspaced short palindromic repeats (CRISPRs) and their associated proteins (Cas) are immune systems in prokaryotes present in most Bacteria and Archaea. They provide adaptive immunity agains …
The clustered regularly interspaced short palindromic repeats (CRISPRs) and their associate …
The Application of the CRISPR-Cas System in Antibiotic Resistance.
Tao S, Chen H, Li N, Liang W. Tao S, et al. Infect Drug Resist. 2022 Aug 2;15:4155-4168. doi: 10.2147/IDR.S370869. eCollection 2022. Infect Drug Resist. 2022. PMID: 35942309 Free PMC article. Review.
There is an urgent need to develop new strategies to control bacterial infections and the spread of antimicrobial resistance. The clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated prote …
There is an urgent need to develop new strategies to control bacterial infections and the spread of antimicrobial resistance. The cluster …
Alternative functions of CRISPR-Cas systems in the evolutionary arms race.
Mohanraju P, Saha C, van Baarlen P, Louwen R, Staals RHJ, van der Oost J. Mohanraju P, et al. Nat Rev Microbiol. 2022 Jun;20(6):351-364. doi: 10.1038/s41579-021-00663-z. Epub 2022 Jan 6. Nat Rev Microbiol. 2022. PMID: 34992260 Review.
In addition, some CRISPR-Cas systems control the expression of genes involved in bacterial physiology and virulence. Moreover, pathogenic bacteria may use their Cas nuclease activity indirectly to evade the human immune system or directly to inv …
In addition, some CRISPR-Cas systems control the expression of genes involved in bacterial physiology and virulence. Mo …
Co-transcriptional DNA and RNA Cleavage during Type III CRISPR-Cas Immunity.
Samai P, Pyenson N, Jiang W, Goldberg GW, Hatoum-Aslan A, Marraffini LA. Samai P, et al. Cell. 2015 May 21;161(5):1164-1174. doi: 10.1016/j.cell.2015.04.027. Epub 2015 May 7. Cell. 2015. PMID: 25959775 Free PMC article.
Immune systems must recognize and destroy different pathogens that threaten the host. CRISPR-Cas immune systems protect prokaryotes from viral and plasmid infection utilizing small CRISPR RNAs that are complementary to the invader's genom …
Immune systems must recognize and destroy different pathogens that threaten the host. CRISPR-Cas immune systems protect …
Application of the CRISPR/Cas System for Generation of Pathogen-Resistant Plants.
Makarova SS, Khromov AV, Spechenkova NA, Taliansky ME, Kalinina NO. Makarova SS, et al. Biochemistry (Mosc). 2018 Dec;83(12):1552-1562. doi: 10.1134/S0006297918120131. Biochemistry (Mosc). 2018. PMID: 30878030 Review.
The use of the CRISPR/Cas9 prokaryotic adaptive immune system has led to a breakthrough in targeted genome editing in eukaryotes. ...The review explores strategies and prospects of the development of pathogen-resistant plants with a focus on the generation of …
The use of the CRISPR/Cas9 prokaryotic adaptive immune system has led to a breakthrough in targeted genome editing in eukaryot …
Francisella novicida CRISPR-Cas Systems Can Functionally Complement Each Other in DNA Defense while Providing Target Flexibility.
Ratner HK, Weiss DS. Ratner HK, et al. J Bacteriol. 2020 May 27;202(12):e00670-19. doi: 10.1128/JB.00670-19. Print 2020 May 27. J Bacteriol. 2020. PMID: 32284320 Free PMC article.
CRISPR-Cas systems are prokaryotic adaptive immune systems that facilitate protection of bacteria and archaea against infection by external mobile genetic elements. The model pathogen Francisella novicida encodes a CRISPR-Cas12a (FnoCas12a) syst …
CRISPR-Cas systems are prokaryotic adaptive immune systems that facilitate protection of bacteria and archaea against i …
CRISPR-Cas, a prokaryotic adaptive immune system, in endodontic, oral, and multidrug-resistant hospital-acquired Enterococcus faecalis.
Burley KM, Sedgley CM. Burley KM, et al. J Endod. 2012 Nov;38(11):1511-5. doi: 10.1016/j.joen.2012.07.004. Epub 2012 Sep 5. J Endod. 2012. PMID: 23063226
INTRODUCTION: Microorganisms are vulnerable to invasion by mobile genetic elements such as viruses, plasmids, and transposons. The recently discovered Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associ …
INTRODUCTION: Microorganisms are vulnerable to invasion by mobile genetic elements such as viruses, plasmids, and transposons. The re …
CRISPR-Cas System: A New Dawn to Combat Antibiotic Resistance.
Rafiq MS, Shabbir MA, Raza A, Irshad S, Asghar A, Maan MK, Gondal MA, Hao H. Rafiq MS, et al. BioDrugs. 2024 May;38(3):387-404. doi: 10.1007/s40259-024-00656-3. Epub 2024 Apr 11. BioDrugs. 2024. PMID: 38605260 Review.
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), an RNA-guided adaptive immune system, protects prokaryotes from foreign DNA like plasmids and phages. ...This review article investigates the …
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), an RNA-guided adaptive …
Role of CRISPR/cas system in the development of bacteriophage resistance.
Szczepankowska A. Szczepankowska A. Adv Virus Res. 2012;82:289-338. doi: 10.1016/B978-0-12-394621-8.00011-X. Adv Virus Res. 2012. PMID: 22420856 Review.
This system has been termed CRISPR/cas and consists of two main components: (i) the CRISPR (clustered, regularly interspaced short palindromic regions) locus and (ii) cas genes, encoding CRISPR-associated (C …
This system has been termed CRISPR/cas and consists of two main components: (i) the CRISPR (clustered, regula …
Survival and Evolution of CRISPR-Cas System in Prokaryotes and Its Applications.
Shabbir MA, Hao H, Shabbir MZ, Hussain HI, Iqbal Z, Ahmed S, Sattar A, Iqbal M, Li J, Yuan Z. Shabbir MA, et al. Front Immunol. 2016 Sep 26;7:375. doi: 10.3389/fimmu.2016.00375. eCollection 2016. Front Immunol. 2016. PMID: 27725818 Free PMC article. Review.
One of these immune systems is clustered regularly interspaced short palindromic repeats (CRISPR). CRISPR-associated proteins play a key role in survival of prokaryotes against invaders, as these systems cleave DNA …
One of these immune systems is clustered regularly interspaced short palindromic repeats (CRISP …
32 results